Ovulation-inducing factor: a protein component of llama seminal plasma

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Ovulation-inducing factor: a protein component of llama seminal plasma

BACKGROUND Previously, we documented the presence of ovulation-inducing factor (OIF) in the seminal plasma of llamas and alpacas. The purpose of the study was to define the biochemical characteristics of the molecule(s) in seminal plasma responsible for inducing ovulation. METHODS In Experiment 1, llama seminal plasma was centrifuged using filtration devices with nominal molecular mass cut-of...

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Biological Characterization of Ovulation-inducing Factor (oif) in Llama Seminal Plasma

The purpose of the studies reported in this thesis was to provide a better understanding of the effects of purified ovulation-inducing factor (OIF) from llama seminal plasma in reflex ovulators (lama glama) and spontaneous ovulators (Bos taurus). The objective of the first study was to determine if the dose of OIF of llama seminal plasma required to elicit ovulation is physiologically relevant,...

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Cetrorelix suppresses the preovulatory LH surge and ovulation induced by ovulation-inducing factor (OIF) present in llama seminal plasma

BACKGROUND The purpose of the study was to determine if the effect of llama OIF on LH secretion is mediated by stimulation of the hypothalamus or pituitary gland. METHODS Using a 2-by-2 factorial design to examine the effects of OIF vs GnRH with or without a GnRH antagonist, llamas with a growing ovarian follicle greater than or equal to 8 mm were assigned randomly to four groups (n = 7 per g...

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Ovulation-inducing factor in seminal plasma: a review.

Ovulation in mammals involves pulsatile release of GnRH from the hypothalamus into the hypophyseal portal system with subsequent release of LH from the anterior pituitary into systemic circulation. Elevated circulating concentrations of LH induce a cascade of events within the mature follicle, culminating in follicle rupture and evacuation. The broad classification of species as either spontane...

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Effect of the Camelid’s Seminal Plasma Ovulation-Inducing Factor/β-NGF: A Kisspeptin Target Hypothesis

Female mammals are classified into spontaneous and induced ovulators based on the mechanism eliciting ovulation. Ovulation in spontaneous species (e.g., human, sheep, cattle, horse, pigs, and most rodents) occurs at regular intervals and depends upon the circulating estradiol. However, in induced ovulators (e.g., rabbits, ferrets, cats, and camelids), ovulation is associated with coitus. In the...

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ژورنال

عنوان ژورنال: Reproductive Biology and Endocrinology

سال: 2010

ISSN: 1477-7827

DOI: 10.1186/1477-7827-8-44